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Reduction in thrombus growth rate depends on platelet derived NO. Perfusions for control (■), insulin, 500 pM (◆), isoproterenol, 100 μM (▲), and samples preincubated with L-NAME [insulin (◇) and isoproterenol (△)] were performed at 100, 1000, and 2000 s-1 (Figures 3A-F). Results represent mean ± s.e.m. of at least five experiments with five separate blood donors.
