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Shear stress causes a slowing of thrombus growth rate that depends of platelet derived NO. Platelet coverage values for each study are the mean ± s.e.m. of 5 separate experiments, each using a different donor. Perfusions for control (■) and L-NAME (□) samples were conducted at 100, 1000, and 2000 s-1 (Figures 4A-C) for 6–10 minutes.
