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Effect of guanylate cyclase on platelet adhesion kinetics. Platelet coverage values for each study are the mean ± s.e.m of 4 separate experiments, each using a different donor. Perfusions were conducted at 1000 and 2000 s-1 (Figures 5A and 5B) for 6 minutes with insulin, 500 pM (■), isoproterenol, 1000 μM (▲) and samples preincubated with guanylate cyclase inhibitor ODQ [insulin (□) and isoproterenol (△)].
