Table 3. Thermodynamic parameters obtained from the DSC profiles of DPPE/DPPG and DPPE/DPPG/CL liposomes in the absence and presence of myxinidin and WMR at lipid/peptide ratio (L/P) = 10.
ΔmH (kJ/mol)a | Tm (°C) | ||
---|---|---|---|
DPPE/DPPG | 57.4 ± 2.5 | 59.0 ± 0.5 | |
+myxinidin | 39.1 ± 3.0 | 58.5 ± 0.5 | |
+WMR | 61.6 ± 3.0 | 58.7 ± 0.5 | |
DPPE/DPPG/CL | 31.1 ± 3.0 | 55.1 ± 0.5 | |
+myxinidin | 26.0 ± 2.5 | 55.2 ± 0.5 | |
+WMR | 50.3 ± 3.0 | 57.1 ± 0.5 |
aValues were normalized against total lipid moles.