Table 1. Correlations between TBL1XR1 expression in tumor tissues and clinical characteristics of stage IV CRCLM patients (Cohort I).

Variables	Cases (n = 47)	TBL1XR1 expression in primary CRC tissues		χ2 test P value	TBL1XR1 expression in liver metastases		χ2 test P value
		Low (n = 20)	High (n = 27)		Low (n = 13)	High (n = 34)
Gender				0.134			0.312
Female	20	6	14		4	16
Male	27	14	13		9	18
Age (year)				0.886			0.248
<60	17	7	10		3	14
≥60	30	13	17		10	20
Primary tumor location				0.095			0.245
Colon	34	17	17		11	23
Rectum	13	3	10		2	11
Primary tumor differentiation				0.381			0.422
Poor	15	5	10		3	12
Well/Moderate	32	15	17		10	22
CRCLM distribution				0.726			0.245
Unilobar	34	15	19		11	23
Bilobar	13	5	8		2	11
No. of CRCLM				0.020*			0.768
<3	34	18	16		9	25
≥3	13	2	11		4	9
Resection Margin				0.270			0.495
R0	39	18	21		10	29
R1	8	2	6		3	5
Adjunctive Chemotherapy				0.366			0.159
Yes	37	17	20		12	25
No	10	3	7		1	9

Abbreviations: TBL1XR1, Transducin (β)-like 1 X-linked receptor 1; CRC, colorectal cancer; CRCLM, colorectal cancer liver metastases.