Table 2. Differentially expressed proteins between normal, degenerating and regenerating zebrafish retina as identified by 2D-DIGE.

Spot No.	Accession	Peptide count	Protein Name	Fold change
				R/D	D/N	R/N
954	B2GP30	17	Fructose-bisphosphate aldolase	2.18	0.51	1.11
604	F1Q8F1	10	Internexin neuronal intermediate filament protein	2.45	0.67	1.64
865	Q7ZUW8	10	Aspartate aminotransferase	2.65	0.29	0.71
866	Q6PC12	5	Enolase 1, (alpha)	2.12	0.34	0.72
1262	Q0D274	16	ES1 protein, mitochondrial	4.28	0.27	1.14
1083	E7F8G7	5	Plectin a	2.21	0.41	0.91
842	Q8AY63	28	Brain-subtype creatine kinase	3.12	0.43	1.35
879	Q6DH07	23	Arrestin 3, retinal (X-arrestin), like	2.20	0.46	1.00
703	Q6IQP5	36	Enolase 1, (Alpha)	2.18	0.48	1.03
876	F1R4Z2	8	Arrestin 3a, retinal (X-arrestin)	2.77	0.34	0.93
704	Q6IQP5	27	Enolase 1, (Alpha)	2.11	0.49	1.03
878	F1R4Z2	15	Arrestin 3a, retinal (X-arrestin	2.72	0.44	1.20
654	Q6NYE1	6	Fibrinogen, B beta polypeptide	0.23	2.95	0.68
1314	E7FES0	13	Apolipoprotein A-Ib	0.19	6.44	1.22
1291	E7FES0	10	Apolipoprotein A-Ib	0.33	2.01	0.66
904	Q6NYE1	9	Fibrinogen, B beta polypeptide	0.12	8.02	0.96
794	X1WCG6	7	Unknown	0.42	2.53	1.05
250	Q5RG12	3	Heat shock protein 90-alpha 2	0.18	4.39	0.80

Protein spots were identified by mass spectrometry analysis.

Proteins which show a 2-fold expression change were considered to be differentially expressed. Fold differences in expression between normal, degenerated and regenerating retina are shown in the table. (Numbers in Bold = 2-fold or more upregulated; Numbers in italics = 0.5-fold or less downregulated). N = normal retina; D = degenerated retina; R = regenerating retina.