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Structural depiction of the potential allosteric coupling trigger going from Site1 to Site2 for the WT hGH to hGHv complexes. The hGHv complex residues are shown in salmon and yellow, respectively. The WT hGH complex residues are shown in green and white, respectively. The hormone and receptor residues are labeled in black and red, respectively. Hydrogen bonds for the hGHv complex are depicted as broken yellow dashes.
