Table 3. Univariate and multivariate proportional hazards analyses of mortality in breast cancer patients according to MCT2 expression levels.
Variables | Univariate HR (95% CI) | P value | Multivariate HR (95% CI) | P value |
---|---|---|---|---|
MCT2 high-risk group (versus low-risk group) | 2.22 (1.03–4.82) | 0.043 | 3.59 (1.28–10.08) | 0.016 |
Age (≥48 years old)* | 0.76 (0.37–1.53) | 0.440 | 0.47 (0.19–1.17 | 0.107 |
Tumour size (>2 cm) | 4.83 (1.16–20.09) | 0.031 | 4.00 (0.49–32.70) | 0.199 |
Lymph-node status (per grade)† | 2.36 (1.38–4.04) | 0.002 | 3.87 (1.77–8.45) | 0.001 |
Grade (per grade) | 0.60 (0.31–1.16) | 0.134 | 1.09 (0.51–2.34) | 0.823 |
Estrogen-receptor positive stain (versus negative group) | 0.40 (0.19–0.81) | 0.012 | 0.10 (0.04–0.29) | <0.0001 |
CI, confidence interval; HR, hazard ratio. Bold entries indicate P value <0.05.
*Median of age: 48 years old.
†Lymph-node positive, 0:0, 1:1∼3, 2: >4.