Figure 3. GSPE can improve the changes in rat myocardial ultrastructure caused by MT.

(a) Normal myocardial cell’s nucleus for reference (15000x). Finely granular appearance of chromatin is present. (b) Trauma group exhibited condensed chromatin in part of nucleus and distributed in the edge of nuclear membrane in blocks (15000x). (c) After drug interference, chromatin condensation of rat myocardial cells was obviously eased, and nuclear morphology had recovered (15000x). (d) Trauma+Vehicle group The nuclear morphology was still abnormal, the nuclear membrane changed in continuity, and the nuclear membrane invaginated and wrinkled (15000x). (e) Normal myocardial cell’s mitochondria for reference (15000x). (f) Myocardial cell’s mitochondria in the trauma group were swollen, and the individual parts of mitochondria were dissolved, showing vacuole formation (15000x). (g) After GSPE interference, mitochondrial swelling was eased and the number of formed vacuoles was reduced (15000x). (h) Trauma+Vehicle group (15000x). n = 3 rats in each group.