Table 4. Methylation in fifteen significantly differentially methylated probes in NR3C1.
Probe | Positiona | Strand | Location | Intron number | Casesb | Controlsc | Delta-betad | p | qvale |
---|---|---|---|---|---|---|---|---|---|
cg15645634 | 142783639 | F | Intron | 8 | 0.0356 | 0.0261 | 0.0095 | 8.31E-06 | 0.000189 |
cg14558428 | 142784982 | R | Intron | 8 | 0.0396 | 0.0314 | 0.0082 | 0.000396 | 0.004514 |
cg17860381 | 142783569 | R | Intron | 8 | 0.0412 | 0.0336 | 0.0076 | 0.00306 | 0.015499 |
cg26464411 | 142784222 | R | Intron | 8 | 0.0556 | 0.0465 | 0.0091 | 0.00406 | 0.017017 |
cg18019515 | 142783385 | R | Intron | 8 | 0.0235 | 0.0192 | 0.0043 | 0.00437 | 0.017388 |
cg18146873 | 142782827 | F | Intron | 8 | 0.0279 | 0.0211 | 0.0068 | 0.00550 | 0.018472 |
cg07733851 | 142781498 | R | Intron | 8 | 0.375 | 0.407 | −0.032 | 0.00573 | 0.018648 |
cg25535999 | 142757312 | R | Intron | 7 | 0.922 | 0.935 | −0.013 | 0.0110 | 0.030167 |
cg18594054 | 142623446 | R | Upstream | 0.926 | 0.939 | −0.013 | 0.0144 | 0.035689 | |
cg04097219 | 142629749 | F | Upstream | 0.972 | 0.978 | −0.006 | 0.0177 | 0.040303 | |
cg06770322 | 142851098 | F | Downstream | 0.960 | 0.966 | −0.006 | 0.0279 | 0.051311 | |
cg23273257 | 142658828 | R | 5′UTR | 0.977 | 0.982 | −0.005 | 0.0279 | 0.051315 | |
cg21702128 | 142784721 | F | Intron | 8 | 0.0516 | 0.0473 | 0.0043 | 0.0306 | 0.053550 |
cg25781210 | 142610141 | F | Upstream | 0.959 | 0.967 | −0.008 | 0.0429 | 0.064421 | |
cg06521673 | 142782072 | R | Intron | 8 | 0.0227 | 0.0201 | 0.0026 | 0.0435 | 0.064851 |
Methylation in fifteen significantly differentially methylated probes (reported as beta-values) in NR3C1 on chromosome 5.
aHuman genome build 37.
bCS patients.
cControls.
dDifference in methylation between cases and controls.
eq-values from multiple correction analysis using a 10% FDR.