Table 5. Methylation in FKBP5, grouped based on GC replacement therapy.
Probe | Positiona | GCRT - yesb | GCRT - noc | Delta_betad | p | qvale |
---|---|---|---|---|---|---|
cg03546163 | 35654363 | 0.484 | 0.588 | −0.104 | 2.99E-06 | 1 |
cg00052684 | 35694245 | 0.514 | 0.550 | −0.036 | 0.00159 | 1 |
cg08586216 | 35612351 | 0.981 | 0.976 | 0.0050 | 0.0122 | 1 |
cg25114611 | 35696870 | 0.314 | 0.339 | −0.025 | 0.0218 | 1 |
cg08915438 | 35697759 | 0.559 | 0.588 | −0.029 | 0.0599 | 1 |
cg16052510 | 35603143 | 0.809 | 0.783 | 0.026 | 0.0995 | 1 |
cg20813374 | 35657180 | 0.442 | 0.462 | −0.020 | 0.109 | 1 |
cg00130530 | 35657202 | 0.690 | 0.710 | −0.020 | 0.115 | 1 |
cg19226017 | 35697185 | 0.752 | 0.770 | −0.018 | 0.137 | 1 |
cg10300814 | 35565116 | 0.948 | 0.953 | −0.0050 | 0.175 | 1 |
cg06087101 | 35551932 | 0.418 | 0.440 | −0.022 | 0.197 | 1 |
cg14642437 | 35652521 | 0.876 | 0.888 | −0.012 | 0.204 | 1 |
cg19014730 | 35635985 | 0.681 | 0.695 | −0.014 | 0.226 | 1 |
cg07843056 | 35656848 | 0.0257 | 0.0229 | 0.0028 | 0.305 | 1 |
cg07485685 | 35696061 | 0.0394 | 0.0375 | 0.0019 | 0.409 | 1 |
cg17085721 | 35645341 | 0.945 | 0.949 | −0.004 | 0.442 | 1 |
cg07061368 | 35631736 | 0.894 | 0.901 | −0.007 | 0.485 | 1 |
cg17030679 | 35696300 | 0.0215 | 0.0227 | −0.0012 | 0.520 | 1 |
cg00610228 | 35695934 | 0.0368 | 0.0359 | 0.0009 | 0.582 | 1 |
cg16012111 | 35656758 | 0.0484 | 0.0500 | −0.0016 | 0.585 | 1 |
cg23416081 | 35693573 | 0.208 | 0.199 | 0.009 | 0.613 | 1 |
cg11845071 | 35695859 | 0.0209 | 0.0202 | 0.0007 | 0.616 | 1 |
cg00140191 | 35656242 | 0.0634 | 0.0615 | 0.0019 | 0.661 | 1 |
cg08636224 | 35657921 | 0.961 | 0.962 | −0.001 | 0.686 | 1 |
cg01294490 | 35656906 | 0.0934 | 0.0913 | 0.0021 | 0.687 | 1 |
cg18726036 | 35543610 | 0.946 | 0.947 | −0.001 | 0.707 | 1 |
cg03591753 | 35659141 | 0.539 | 0.534 | 0.005 | 0.720 | 1 |
cg14284211 | 35570224 | 0.139 | 0.134 | 0.005 | 0.738 | 1 |
cg06937024 | 35695489 | 0.0259 | 0.0264 | −0.0005 | 0.791 | 1 |
cg00862770 | 35655764 | 0.0256 | 0.0251 | 0.0005 | 0.795 | 1 |
cg02665568 | 35544468 | 0.921 | 0.923 | −0.002 | 0.799 | 1 |
cg07633853 | 35569471 | 0.155 | 0.157 | −0.002 | 0.829 | 1 |
cg15929276 | 35687457 | 0.187 | 0.186 | 0.001 | 0.911 | 1 |
cg10913456 | 35656590 | 0.0175 | 0.0175 | 0.000 | 0.989 | 1 |
Summary of methylation (reported as beta-values) in FKBP5 on chromosome 6. GCRT = glucocorticoid replacement therapy.
aHuman genome build 37.
bPatients receiving GCRT.
cPatients not receiving GCRT.
dDifference in methylation between patients receiving GCRT and those not receiving such therapy.
eq-values from multiple correction analysis using a 10% FDR.