Table 1. Example of recent published works on small molecule detection exploiting POC-compliant detection methods.
Target | Analytical method† | LOD | Linear range | References |
---|---|---|---|---|
Acetaminophen | Amperometry and DPV | 2.1 nM | 5 nM to 800 μM | 36 |
Adenosine | EIS | 20 fM | 0.05 pM to 17 pM | 37 |
Bisphenol A | FET | 56 pM | 1 to 104 fM | 38 |
Chloramphenicol | SWV | 5 nM | 40 to 1000 nM | 39 |
Cocaine | DPV | 0.13 nM | 0.1 to 10 nM | 40 |
17β-estradiol | FET | 50 nM | 50 nM to 1.6 μM | 28 |
Etoposide | DPV | 5.4 nM | 20 nM to 2 μM | 41 |
Etoposide | SWV | 1.29 μM | 10 to 60 μM | 42 |
Glucose | SWV | 4 mM | 4 to 20 mM | 43 |
Glucose | FET | 2 mM | 2 to 8 mM | 44 |
Kanamycin | SWV | 14 pM | 10 nM to 2 μM | 45 |
Naproxen | CV | 16 μM | Up to 300 μM | 12 |
Oxytetracycline | SWV | 0.22 nM | 1.1 pM to 110 nM | 46 |
Rifampicin | Amperometry | 50 nM | 2 to 14 μM | 47 |
Streptomycin | SWV | 10 nM | 50 to 1000 nM | 39 |
Tenofovir | FET | 1.2 nM | 1 nM to 100 nM | This work |
Tenofovir | SWCAdSV | 1.3 μM | 1.7 to 17.4 μM | 48 |
Theophylline | CV | 50 nM | Up to 120 μM | 49 |
†CV = Cyclic Voltammetry; SWV = square wave voltammetry; FET = field effect transistor; EIS = electrochemical impedance spectroscopy; DPV = differential pulse voltammetry; EMAT = electromagnetic acoustic transducer; LSV = linear sweep voltammetry; SWCAdSV = square-wave cathodic adsorptive stripping voltammetry.