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. 2017 Mar 15;7:44302. doi: 10.1038/srep44302

Figure 5. Major metabolic pathways affected by different ROL gene dosage in P. pastoris cells growing in chemostat cultures using a glycerol/methanol mix as a carbon source.

Figure 5

Glycerol uptake pathway (blue), tricarboxylic acid (TCA) cycle (orange), fatty acid metabolism (synthesis and β-oxidation) (brown), methanol assimilation (purple) and peroxisomal protein import (grey) are represented. Gene regulation in each step is indicated by a colour gradient. Unregulated genes are showed in grey.