Table 2. Comparison of the statistical results of the preclinical validations of the 3-plex immunoassays based on the QDEM and Luminex xMAP® technologies for the diagnosis of lung cancer.
Immunoassay | Marker | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|---|
P value | AUC | Model AUC | Model P value | ||
QDEM | AMBP | <0.05 | 0.899 | 0.992 | <0.05 |
PRDX2 | <0.05 | 0.747 | |||
PARK7 | <0.05 | 0.192 | |||
xMAP® | AMBP | <0.05 | 0.947 | 0.989 | <0.05 |
PRDX2 | <0.05 | 0.709 | |||
PARK7 | <0.05 | 0.152 |
AMBP, α-1-microglobulin/bikunin precursor; AUC, area under the curve; LoQ, limit of quantification; PRDX2, peroxiredoxin 2; PARK7, Parkinson disease protein 7; QDEM, quantum dot encoded microspheres.