Fig. 5.

Treatments that change slo expression alter drug responsiveness. (A) Recovery of WT flies from 0.3% benzyl alcohol sedation after pretreatment with chloroform compared with nonpretreated control flies. (B) Recovery of WT flies from 0.3% benzyl alcohol after pretreatment with 0.15, 0.3, or 0.4% benzyl alcohol compared with nonpretreated control flies. * indicates that the 0.3 and 0.4% pretreatments are significantly different (**, P < 0.01) from control (whereas the 0.15% pretreatment is not). (C) Recovery of WT flies from 0.3% benzyl alcohol sedation after pretreatment with toluene compared with nonpretreated control flies. (D and E) Recovery of WT flies from 0.3% benzyl alcohol sedation after pretreatment with CO₂ (D) or heat followed by CO₂ (E) compared with nonpretreated control flies. (F) Recovery of WT flies from benzyl alcohol after pretreatment with heat and CO₂ compared with flies pretreated with heat. In A, C, and F, * indicates that the recovery curves are significantly different from control (*, P < 0.05; **, P < 0.01). (Error bars are SEM calculated for each data point.)