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. 2017 Mar 16;14:6. doi: 10.1186/s12987-017-0055-4

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Increased mRNA expression of Abcc1, Abcc2 and Abcc4 at the BBB following H/R. Female Sprague–Dawley rats were subjected to H/R (Hx = 6% O₂, 1 h; R = 21% O₂ for 10 min, 30 min or 1 h), normoxia (Nx), hypoxia (Hx), or administered the Nrf2 activator sulforaphane for 3 h. Results are expressed as mean ± SD of three experiments, with each group consisting of pooled microvessels from three individual animals. *p < 0.01