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. 2017 Mar 15;11:37. doi: 10.1186/s12918-017-0414-4

Table 2.

Overview of culture condition at RNA sampling

# Cell line Conditiona μ [h−1] td [h] qIgG Time [h]
1.1 CHO-K1 Exponential phase 0.0353 19.6 0 24
1.2 CHO-K1 Stationary phase 0.001 693.1 0 120
2.1.1 CHO DG44 IgG Exponential phase 0.0231 30.0 9.93 48
2.1.2 CHO DG44 IgG Stationary phase 0.0008 866.4 8.28 140
2.2.1 CHO DG44 IgG Exponential phase, 0% NEAA 0.0235 29.5 8.46 48
2.2.2 CHO DG44 IgG Stationary phase, 0% NEAA 0.0094 73.7 8.42 130
2.3.1 CHO DG44 IgG Secretory stress by NaBu 0 −99.0 11.86 70
2.3.2 CHO DG44 IgG Secretory stress by NaBu 0 −138.6 17.12 100

aCondition at the time point of RNA sampling, μ: Specific growth rate, td: Doubling time, qIgG: Specific IgG production rate, Time: Time of cultivation