Table 2.
Comparison between PP and PA (both without neoadjuvant chemotherapy)
| Metabolite | No neoadjuvant chemotherapy | Mean (nmol/mg) | p value |
|---|---|---|---|
| Ascorbate | PP | 0.3488 ± 0.2191 | 0.4454 |
| PA | 0.3988 ± 0.2221 | ||
| Aspartic acid | PP | 0.7577 ± 0.3284 | 0.2926 |
| PA | 0.6229 ± 0.2255 | ||
| Choline | PP | 1.5580 ± 0.5921 | 0.0014 |
| PA | 0.8849 ± 0.3887 | ||
| Creatine | PP | 1.7371 ± 0.9568 | 0.5047 |
| PA | 1.3561 ± 0.5057 | ||
| Ethanolamine | PP | 0.9314 ± 0.4502 | 0.0226 |
| PA | 0.6188 ± 0.2620 | ||
| Glutamate | PP | 2.9830 ± 0.8698 | 0.1114 |
| PA | 2.4650 ± 0.7699 | ||
| Glycerol | PP | 8.1840 ± 7.3988 | 0.0037 |
| PA | 2.2750 ± 1.1994 | ||
| Glycine | PP | 6.0920 ± 5.0908 | 0.0005 |
| PA | 2.2663 ± 0.8577 | ||
| Glycerophosphocholine | PP | 2.4215 ± 2.6084 | 0.3516 |
| PA | 1.0319 ± 0.5029 | ||
| Lactate | PP | 11.0040 ± 2.4733 | 0.0006 |
| PA | 16.1370 ± 4.7272 | ||
| Phosphorylcholine | PP | 1.1696 ± 0.6396 | 0.5201 |
| PA | 0.9764 ± 0.5008 | ||
| Taurine | PP | 2.9660 ± 1.9594 | 0.0021 |
| PA | 4.4630 ± 1.4063 | ||
| Threonine | PP | 1.1202 ± 0.2821 | 0.6512 |
| PA | 1.1931 ± 0.4230 | ||
| Glutamine | PP | 0.6855 ± 0.2518 | 0.6859 |
| PA | 0.6394 ± 0.2272 | ||
| Succinic acid | PP | 0.3068 ± 0.2121 | 0.1786 |
| PA | 0.1762 ± 0.0763 | ||
| Glucose | PP | 1.2247 ± 0.6158 | 0.7937 |
| PA | 1.3141 ± 1.1020 | ||
| Tyrosine | PP | 0.0521 ± 0.0443 | 0.0583 |
| PA | 0.0741 ± 0.0472 | ||
| Phenylalanine | PP | 0.1449 ± 0.0771 | 0.0866 |
| PA | 0.0741 ± 0.0811 |
Results of the Mann-Whitney U test. Metabolite differences between PP and PA, both without neoadjuvant chemotherapy (univariate analysis, nonparametric test)
p <0.05 are in boldface