Table 2.

Outcomes to be measured

Outcome	Instrument/Measurement
Glucose Tolerance	75gram, 2-hour Oral Glucose Tolerance Test
Insulin Sensitivity	Whole-Body Insulin Sensitivity Index
Insulin Secretion	Insulinogenic Index
β-cell function	Oral Disposition Index
Quality of Life	Youth Quality of Life, Weight-Specific Quality of Life
Total body composition (fat, muscle, and bone)	Dual-energy X-Ray Absorptiometry
Whole-abdominal fat distribution (subcutaneous abdominal adipose tissue, visceral adipose tissue, organ fat)	Magnetic Resonance Imaging
Physical Activity	3 Day Physical Activity Recall
Cardiorespiratory Fitness (Vo2peak)	Submaximal Exercise Test
Dietary Intake	2007 Block Food Screener