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Tacromilus immune suppression can impact PyMT tumor latency in the C56BL/6 background. PyMT C56BL/6 mice were implanted at age (A) 43 d or (B) 77 d with a 13 mg biodegradable 90 d-releasable tacrolimus or placebo pellet in the interscapular region of the back, and tumor onset was recorded over time.
