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Frs2α2F/2F mice exhibit defective early and late eye development. Hematoxylin/eosin-stained sections through the eye region of embryos of the indicated ages and genotypes. lpl, lens placode; ple, presumptive lens ectoderm; ov, optic vesicle; lp, lens pit; pr, presumptive retina; lv, lens vesicle; rpe, retinal pigment epithelium. In L the dashed red line indicates the boundary of pigment epithelial tissue.
