Table 1.
Baseline demographics and clinical characteristics
| Never smokers | Smokers w/o COPD | COPD GOLD I | COPD GOLD II-III | COPD GOLD IV | p ANOVA | |
|---|---|---|---|---|---|---|
| Subjects (n) | 7 | 6 | 6 | 13 | 10 | |
| Gender (female/male) | 5/2 | 4/2 | 3/3 | 2/11 | 6/4 | |
| Age (years) | 63 ± 4.8 | 57 ± 3.3 | 67 ± 2.9 | 68 ± 1.9 | 61 ± 1.4 | ns |
| Height (m) | 1.64 ± 0.1 | 1.71 ± 0.1 | 1.74 ± 0.1 | 1.73 ± 0.1 | 1.69 ± 0.1 | ns |
| Weight (kg) | 65 ± 4.6 | 69 ± 4.6 | 69 ± 5.7 | 73 ± 3.1 | 65 ± 1.7 | ns |
| Body mass index | 24 ± 1.3 | 24 ± 1.0 | 23 ± 1.2 | 24 ± 1.1 | 23 ± 1.0 | ns |
| Pack years | N/A | 43 ± 8.2 | 40 ± 7.6 | 48 ± 3.3 | 41 ± 3.9 | ns |
| Smoker/ex-smoker | N/A | 4/2 | 3/3 | 5/8 | 0/10 | |
| FEV1/FVC | 86 ± 5.7 | 79 ± 2.0 | 67 ± 0.9 | 55 ± 2.8 | 32 ± 2.0 | <0.001 |
| %FEV1 | 110 ± 6.2 | 98 ± 6.0 | 87 ± 2.3 | 64 ± 3.1 | 23 ± 1.4 | <0.001 |
| Corticosteroids (yes/no/unknown) | 0/7/0 | 0/6/0 | 0/6/0 | 2/11/0 | 9/0/1 | |
| Bronchodialator (yes/no/unknown) | 0/7/0 | 0/6/0 | 3/3/0 | 3/10/0 | 9/0/1 |
Values are mean ± standard error of mean
COPD chronic obstructive pulmonary disease, FEV 1 forced expiratory volume in 1 s, (F)VC (forced) vital capacity, GOLD Global Initiative for Chronic Obstructive Lung Disease