Fig. 3.

met mutant mice develop unique tumor profiles. (A) Hemangiosarcoma observed s.c. in a D1226N^mu/mu mouse. (B) Transitional cell carcinoma of the ureter observed in a M1248T^mu/+ mouse. (C) Squamous cell carcinoma of the anus observed in a M1248T^mu/+ mouse. (C) Adjacent myxoma (M) and hemangiosarcoma (H) observed in a Y1228C^mu/+ mouse. (E and F) Primary fibrosarcoma from a M1248T/L1193V^mu/+ mouse (E) and the metastatic lesion (M) in the lung (L) (F). (Hematoxylin/eosin images, ×200 magnification.)