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Treatment of NTHi clinical strain biofilms with clarithromycin. A range of concentrations of clarithromycin were used to treat pre-established 24 h static biofilms. The results show the means with SEM of three experiments each done in triplicate. Statistical significance was determined by one-way ANOVA comparing the antibiotic-treated biofilms with the vehicle control (*P < 0.05; **P < 0.01; ***P < 0.001). The dashed line indicates the LOD.
