Table 2.
Distribution of systemic infection in internal organs of LDLRnull mice.
| Bacterial infection | Positive systemic tissue samples | |||||
|---|---|---|---|---|---|---|
| Number of organs sampled by PCR | ||||||
| Heart | Aorta | Liver | Spleen | Kidney | Lung | |
| (n = 11) | (n = 8) | (n = 11) | (n = 5) | (n = 11) | (n = 11) | |
| Fusobacterium nucleatum | 3 | 1 | 1 | 0 | 3 | 2 |
| Porphyromonas gingivalis | 6 | 4 | 3 | 0 | 1 | 4 |
| Treponema denticola | 5 | 3 | 1 | 0 | 0 | 1 |
| Tannerella forsythia | 3 | 1 | 1 | 0 | 0 | 0 |
| Sham infection | 0 | 0 | 0 | 0 | 0 | 0 |
To analyze intravascular infection of systemic organs (heart, aorta, liver, spleen, kidney, lungs), total DNA from each perspective organ was isolated and examined for four bacterial genomic DNA by PCR using appropriate species-specific primers.