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Ex vivo HC gp-39-directed immune responses can suppress other immune responses. (A) HC gp-39-activated PBMCs are able to suppress IFN-γ responses to recall antigens in three different healthy donors. (B) HC gp-39-stimulated HLA-A2+ PBMCs from three different healthy donors are capable of suppressing IFN-γ production of activated HLA-A2+ CTLs. **, P < 0.005; ***, P < 0.0005.
