Table 2.

Characteristics of colorectal cancer patients with and without a concomitant diagnosis of infective endocarditis, SEER-Medicare 1992–2009.

	No endocarditis (N=167,699)	Endocarditis (N=191)
Median age (interquartile range)	77 (71–83)	78 (72–83)
Female, %	53.3	38.2
Race, %
White	86.5	89.5
African American	8.9	*
Asian/Pacific islander	4.2	*
Other/unknown/unspecified	0.5	*
Comorbidity score1, %
0	52.7	39.3
1	21.3	>17.2
2+	14.9	37.7
Unknown	11.0	<5.8
Structural cardiac condition1, %	10.6	34.6
Intravascular device1, %	3.0	10.5
End stage renal disease1, %	0.8	*
Sentinel symptom2, %
Anemia	26.4	42.9
Gastrointestinal bleeding	24.1	29.3
Gastrointestinal symptoms	17.7	19.9
Large bowel obstruction	2.4	*
Stage, %
I	26.8	38.2
II	31.5	32.5
III	25.0	19.9
IV	16.8	9.4
Grade of differentiation, %
Well differentiated	8.9	13.6
Moderately differentiated	63.9	62.3
Poorly differentiated	19.2	17.8
Unknown	8.0	6.3
Location, %
Ascending colon	35.3	31.4
Transverse colon	14.5	16.7
Descending colon	27.1	26.7
Rectum	23.1	25.1
Urbanicity, %
Big metro (≥1 million)	54.0	58.6
Metro (250,000–1 million)	28.4	29.3
Urban (20,000–250,000)	6.2	*
Less urban (2500–20,000)	9.3	*
Rural (rural or <2500)	2.2	*
SEER registry census region, %
West	38.2	37.2
Northeast	20.5	34.0
Midwest	19.0	12.0
South	20.7	16.2
Pacific	1.6	*
Year of CRC diagnosis, %
1992–1996	19.0	18.9
1997–2001	26.1	20.4
2002–2006	30.4	30.9
2007–2010	24.5	29.8
Census tract features [median (interquartile range)]
% did not complete high school	16.7 (10.0–27.1)	15.5 (8.9–24.3)
% below poverty line	8.4 (4.5–15.6)	7.0 (4.0–11.6)
% black race/ethnicity	2.1 (0.6–8.3)	2.1 (0.7–6.7)
% English not well/at all at 65+	1.5 (0–5.4)	2.1 (0–5.9)
Median income (USD)	42,219 (31,906– 57,068)	49,131 (35,334– 62,316)

^*Cells with counts of 11 or lower (≤ 5.8%) are blinded following SEER-Medicare privacy policy

¹Evaluated the 6^th month before colorectal cancer diagnosis.

²Evaluated during the 3 months preceding colorectal cancer diagnosis.

³Missing in 1296 individuals.