Figure 1. Body weights of diabetic ZDSD (●), non-diabetic ZDSD (■) and SD (▲) rats over the course of the study. The shaded bar indicated the period of time when all of the groups of animals were on the diabetogenic diet (5SCA). The more obese ZDSD rats became diabetic when placed on the diabetogenic diet versus the non-diabetic ZDSD and SD controls. At the initiation of the diabetogenic 5SCA diet, the ZDSD rats that became diabetic weighted significantly more (p≤0.05) than both the ZDSD rats that did not become diabetic and the SD rats. The ZDSD rats however, that did not become diabetic weighed significantly more (p≤0.02) than the SD rats. This trend persisted during and after the time that animals were provided the 5SCA diet and the 5008 diet; however, by the time of euthanasia, there was no significant difference between the weight of diabetic and non-diabetic ZDSD rats. Both groups of ZDSD rats weighed significantly more (p≤0.02) than SD rats at the time of euthanasia. The * symbol indicates significantly greater body weight compared to non-diabetic ZDSD and SD rats; and the + symbol indicates significantly greater body weight compared to SD rats.