Figure 3. Wound healing analysis over the course of the study. There were no significant differences in mean wound diameter between any groups until day 7 after injury; however, diabetic (●) and non-diabetic ZDSD (■) rats had significantly (p≤0.05) larger wounds than SD (▲) rats on days 9 and 11, as well as on day 14 (p<0.01). Wound size between diabetic and nondiabetic ZDSD rats did not differ significantly at any experimental time point. The * symbol indicates significant difference of p≤0.05, and the + symbol indicates significant difference of p≤0.01.