Table 5. NR4A2 is a candidate transcription factor affected by the variant rs#.
Factor | AAGACCACGTCAC | AAGACCATGTCAC | AAGACCAGGTCAC |
---|---|---|---|
NR4A2 | 0.876 | 0.762 | 0.820 (0.866) |
ATF1 | 0.910 | 0.779 | 0.759 |
ZNF354C | 0.887 | 0.712 | 0.755 |
MEIS1 | 0.906 | 0.970 | 0.757 (0.702) |
RORA | 0.743 | 0.743 | 0.865 |
The five transcription factors (TFs) that recognize the region surrounding rs#41310367 are in the first column. The second column lists the JASPAR [26] scores for the reference sequence in humans. The third column lists the scores for the sequence with the minor T allele, and the last column lists the scores with the G variant at the same position, which is the consensus sequence in many vertebrates.