Table 1. Acquisition times and cross-link densities at different FDR rate.
Target protein | MS acquisition
time |
Links per residue
at 5% FDR (number of residue pairs) |
Links per residue at
10% FDR (number of residue pairs) |
Links per residue at
20% FDR (number of residue pairs) |
---|---|---|---|---|
HSA (585 AA) | 12 days | 0.85 (500) | 1.51 (881) | 2.56 (1495) |
Tx781 (420 AA) | 4.7 days | 0.73 (305) | 1.06 (444) | 1.35 (565) |
Tx808 (418 AA) | 4.4 days | 0.63 (265) | 0.68 (286) | 0.82 (342) |
Tx767 (318 AA) | 4.0 days | 1.20 (381) | n.d. | 2.26 (718) |
Tx812 (204 AA) | 3.8 days | 0.99 (201) | 1.30 (265) | 1.77 (360) |