Table 4. Genotype-phenotype correlation of SNPs with risk factors of UC.
| SNP/Geno-type | Sex | Age at Diagnosis (Yrs.) | Disease Extent | Smoking history | Social Status | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Male | Female | 15–40 | >40 | Proctitis | Procto-sigmoditis | LeftSided Colitis * | Pancolitis | Yes | No | Urban | Rural | |
| CC/TT (W) | 110 | 75 | 123 | 62 | 22 | 47 | 41 | 75 | 17 | 168 | 94 | 91 |
| CT/TC (M) | 6 | 3 | 4 | 5 | 0 | 2 | 5 | 2 | 1 | 8 | 5 | 4 |
| Total | 116 | 78 | 127 | 67 | 22 | 49 | 46 | 75 | 18 | 176 | 99 | 95 |
| MAF (%) | 5.17 | 3.85 | 3.15 | 7.46 | 0 | 4.08 | 10.87 | 2.67 | 5.56 | 4.54 | 5.05 | 4.21 |
MAF- Minor allele Frequency, Yr-years, W-wild, H-Heterozygous, M-Mutant
* Left sided colitis showed positive association with UC p = 0.03, OR = 4.39 (1.13–17.01).