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. 2017 Mar 1;37(9):2305–2316. doi: 10.1523/JNEUROSCI.2414-16.2016

Table 1.

Loss of YFP+/TH+ cells in the central mDA region of Neurod6Cre/Cre;R26RYFP/YFP mutants per brain hemispherea

E18.5 P3 P14 Adult
n 3 3 3 3
Neurod6 controls (mean ± SEM) 200 ± 3 232 ± 5 207 ± 1 270 ± 16
Neurod6 mutants (mean ± SEM) 211 ± 27 167 ± 10 143 ± 14 185 ± 26
% of YFP+/TH+ mDA cells lost in mutants relative to controls NA 28 31 32
Average no. of cells lost in mutants (mean ± SEM) NA 65 ± 14 65 ± 14 85 ± 15
Significance NS ** ** *
p value 0.69 0.004 0.001 0.05

aRaw data of the numbers of mDA neurons counted per brain hemisphere in the central mDA region and the results from statistical analysis, comparing cell counts between Neurod6 mutant and control brains at each stage using the unpaired Student's t test. n, Number of brain samples analyzed; NA, not applicable; NS, not significant.

*p < 0.05 (Student's t test);

**p < 0.005 (Student's t test).