Fig 6. Histological analysis of F4 wt and Tg mice at weaning and adulthood.

F₄ mammary gland slices from 3 week old (weaning) or 16 week old (adult) virgin female wt or Tg mice were stained with hematoxylin/eosin (A). S, stroma; E, epithelium; L, lumen; Ad, adipocyte. The epithelium thickness, the stromal thickness and lumen diameter of mammary ducts were measured in wt or Tg mice at weaning (B) and adulthood (C). Scale bar, 15 μm. Each bar represents mean ± S.E.M. N>5 per group. *: P <0.05, ***: P <0.001.