Fig 6. Full Width at Half Maximum (FWHM) was calculated as a measure of temperature distribution at the end of each sonication in tissue-mimicking phantoms.
a. Varying acoustic power, significant differences in FWHM were found between 550 and 650 W, as well as for 600 and 650 W (p≤0.05). b. Comparing the number of cycles/pulse, significant differences were found between 10,000 cycles/pulse and 20,000 cycles/pulse (p = 0.042). Other parameters showed no differences in FHWM. c. Total sonication was varied from 137 to 820 seconds and no significant difference was found in the FWHM between any parameters (p > 0.05). d. Varying PRF from 0.5 Hz to 5 Hz resulted in significant differences in FWHM between 0.5 and 2, 3, 4, and 5 Hz. Similarly, significant differences were found between 1 and 2, 3, 4, and 5 Hz (p ≤ 0.05). No significant differences were found between any other parameters.