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. 2017 Mar 16;12(3):e0173913. doi: 10.1371/journal.pone.0173913

Fig 8. Effect of c-KIT overexpression on cell morphological characteristics.

Fig 8

Four principal malignancy features were more represented in empty vector transfected cells (A) than c-KIT overexpressing cells (B): high nuclear-cytoplasmic ratio (black thick arrows); presence of powdery chromatin pattern, sometimes with clumps (black thin arrows) presence of macro and multiple nucleoli (white thick arrows) cells presenting more nuclei (2 or 3).