Fig 8. Effect of c-KIT overexpression on cell morphological characteristics.
Four principal malignancy features were more represented in empty vector transfected cells (A) than c-KIT overexpressing cells (B): high nuclear-cytoplasmic ratio (black thick arrows); presence of powdery chromatin pattern, sometimes with clumps (black thin arrows) presence of macro and multiple nucleoli (white thick arrows) cells presenting more nuclei (2 or 3).