Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Mar 6;13(3):e1006266. doi: 10.1371/journal.ppat.1006266

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 Xu et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PMC Copyright notice

Fig 2 — (A) Heatmap of 1,770 genes differentially expressed between NS1-S1 and NS1^mTAD2-S1 cell lines (Gene set 5). First, genes differentially expressed between NS1-S1 cell lines treated with and without Dox (NS1-S1 Dox+/-; Gene set 1) and between both NS1-S1 and NS1^mTAD2-S1 cell lines treated with Dox (NS1-S1/Dox+ and NS1^mTAD2-S1/Dox+; Gene set 2) were identified. Gene set 3 contains overlapped differential genes both in Gene sets 1 and 2. Next, genes differentially expressed between NS1^mTAD2-S1 cells treated with and without Dox (NS1^mTAD2-S1 Dox+/-) were identified as Gene set 4. Finally, Gene set 5, which represents the genes regulated by NS1 TAD2, was obtained by subtracting Gene set 4 from Gene set 3, and is shown. (B) Heatmap of 23 KEGG cell cycle genes showing significant differential expression between NS1-S1/Dox+ and NS1^mTAD2-S1/Dox+ (Q value < 0.05 and fold change ≥ 1.5). Each column represents gene expression data for a NS1-S1 or a NS1^mTAD2-S1 cell line (n = 3/cell line). Each row represents a gene. Red indicates increased expression. Blue indicates decreased expression.