Table 1. Clinicopathological characteristics of 95 breast cancer patients.
| Characteristics | Number of patients, n (%) | Number of patients with AKT1 promoter mutations, n (%)1 | P value2 | |
|---|---|---|---|---|
| Molecular subtype | Basal-like | 11 (11.58) | 3 (13.04) | 0.656 |
| HER2-enriched | 10 (10.53) | 2 (8.70) | ||
| Luminal A | 24 (25.26) | 5 (21.74) | ||
| Luminal B | 45 (47.37) | 13 (56.52) | ||
| Unknown | 5 (5.26) | 0 (0) | ||
| ER status | Positive (+) | 70 (73.68) | 18 (78.26) | 0.764 |
| Negative (-) | 25 (26.32) | 5 (21.74) | ||
| PR status | Positive (+) | 59 (62.11) | 14 (60.87) | 1 |
| Negative (-) | 36 (37.89) | 9 (39.13) | ||
| HER2 status | Positive (+) | 23 (24.21) | 5 (21.74) | 0.951 |
| Negative (-) | 60 (63.16) | 15 (65.22) | ||
| unknown | 12 (12.63) | 3 (13.04) | ||
| Lymph metastasis | Yes | 34 (35.79) | 8 (34.78) | 1 |
| No | 61 (64.21) | 15 (65.22) | ||
| Age | ≥50 | 50 (52.63) | 11 (47.83) | 0.772 |
| <50 | 45 (47.37) | 12 (52.17) | ||
Note:
1 the percentage was calculated in 23 patients with AKT1 promoter mutations;
2 P values were calculated between mutated and non-mutated patients using the Chi-square test.