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. 2017 Mar 16;12(3):e0174038. doi: 10.1371/journal.pone.0174038

Fig 6. Adjuvant effect of imiquimod on induction of tumor regression and promotion of survival by GTL001.

Fig 6

Solid tumors were induced by subcutaneous injection of C57BL/6 mice with HPV16 E7-expressing TC-1 cells. On day 11, when tumors were at least palpable, and again on day 39, mice (10/group) were vaccinated intradermally with 10 μg of the solution or powder formulation of GTL001. Where indicated, mice also received 25 mg imiquimod cream/ear at the vaccination site immediately and 24 h after each vaccination (days 11, 12, 39, and 40). Symbols indicate % full tumor regression for each group of 10 mice, and horizontal bars indicate means.