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The representative images and the detailed biodistribution data (A and C) in vivo and (B and D) ex vivo of HCT116 tumor-bearing models after intragastric administration of free DiR and DiR-labeled liposomes.
Notes: The red arrows in (A) indicate the location of HCT116 tumors. *P<0.05; **P<0.01.
Abbreviations: DiR, 1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindotricarbocyanine iodide; Lipo, liposomes; PEG, polyethylene glycol; cRGD, cyclic arginylglycylaspartic acid.
