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. 2017 Mar 10;9:63–75. doi: 10.2147/HIV.S120576

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© 2017 Dlamini and Hull. This work is published and licensed by Dove Medical Press Limited

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Position of splicing enhancers and silencers as well as the proteins that target these sites.

Notes: Negative regulation sites are marked in orange, whereas positive regulators of splicing are marked in green. The sequences of the acceptor sites as well as their positions and the regulatory elements and factors associated with each site are given in the table below the figure.

Abbreviations: ESS, exonic splicing silencer; ESE, exonic splicing enhancer; ESSV, exonic splicing silencer; hnRNP, heterogeneous nuclear ribonucleoprotein; ISS, intronic splicing silencer; GAR, guanosine–adenosine rich.