Table 5.

Clusters showing bivariate associations of age and slow wave activity (SWA) with regional cerebral metabolic rate of glucose uptake (rCMRglu)

Predictor	Hemisphere	Significant cluster regions	Peak MNI coordinates	Max cluster size	R2D	t	Z	df	P
Age (negative)	Right	Inferior frontal	54, 16, 26	11 295	0.22	−4.12	−3.81	1, 50	0.009†
	Right	Superior frontal	30, 6, 62
	Left	Supplementary motor area	0, 6, 54
Age (positive)	Bilateral	Cerebellum	8, −40, −24	27 031	0.32	4.30	3.95	1, 50	<0.001
	Bilateral	Parietal white matter	−30, −32, 34
aSWA			−6, −6, 74	3283	0.17	3.14	2.99	1, 50	0.59
rSWA (positive)	Left	Inferior frontal	−34, 14, 32	10 598	0.20	4.81	4.34	1, 50	0.013†
	Bilateral	Superior frontal	8, 28, 52
	Bilateral	Precentral	−36, 0, 54
Age 9 aSWA	Left	Middle temporal gyrus	−38, −64, 18	32 106	0.31	4.68	4.23	1, 48	<0.001*,†
	Bilateral	Posterior cingulate/BA 31	10, −28, 44
	Right	Medial frontal gyrus	14, 52, −2
Age 9 rSWA			−24, −54, 56	1026	0.13	2.66	2.56	1, 48	0.998

aSWA, absolute SWA; rSWA, relative SWA.

^*Significance after controlling for age.

^†significance after controlling for grey matter volume. MNI coordinates and t-values represent peak-level statistics. Cluster size and P-values represent family-wise error (few)-corrected cluster-level statistics.