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Specimen of core needle biopsy of the lesion shows a rigid lesion.
Notes: The microscopic analysis shows (A) epithelioid granulomatous process with giant cells induced by silicone (B–E). CD68 immunohistochemistry positivity, denoting histiocytic nature of cells. The diagnosis was confirmed as SIGBIC. Magnification for (B) ×40; (C) ×500; (D) ×100; (E) ×500.
Abbreviation: SIGBIC, silicone-induced granuloma of breast implant capsule.
