TABLE I. Serogroup C meningococcal disease incidence by age group and region of residence (Brazil, 2001-2013).
| Region | Age group (years) | Meningococcal disease serogroup C incidence (cases/100,000) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||||||
| 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011* | 2012* | 2013* | ||
| < 1 | 3.98 | 2.84 | 4.67 | 6.24 | 6.19 | 7.71 | 6.92 | 7.09 | 8.78 | 9.50 | 4.15 | 2.82 | 3.03 | |
| 1-4 | 2.26 | 1.85 | 2.18 | 2.77 | 2.96 | 3.13 | 2.78 | 3.40 | 3.89 | 3.68 | 3.16 | 1.70 | 0.89 | |
| Brazil | 5-9 | 0.95 | 1.06 | 0.90 | 1.50 | 1.41 | 1.61 | 1.61 | 1.71 | 2.00 | 2.03 | 1.87 | 2.05 | 1.42 |
| ≥ 10 | 0.23 | 0.25 | 0.26 | 0.37 | 0.36 | 0.38 | 0.43 | 0.54 | 0.62 | 0.71 | 0.70 | 0.71 | 0.58 | |
| Total | 0.53 | 0.50 | 0.54 | 0.76 | 0.75 | 0.81 | 0.81 | 0.95 | 1.09 | 1.15 | 1.01 | 0.91 | 0.70 | |
|
| ||||||||||||||
| < 1 | - | - | - | 0.49 | 1.59 | - | - | 1.86 | - | 1.63 | - | 1.30 | 1.60 | |
| 1-4 | 0.48 | 0.68 | 0.27 | 0.33 | 0.20 | 1.21 | 0.54 | - | 0.92 | 0.48 | 0.70 | 0.42 | 0.22 | |
| North | 5-9 | 0.18 | 0.70 | 0.69 | 1.16 | - | 0.23 | 1.06 | 0.22 | 0.56 | - | 0.22 | 0.42 | 0.22 |
| ≥ 10 | 0.32 | 0.22 | 0.17 | 0.35 | 0.03 | 0.20 | 0.27 | 0.38 | 0.47 | 0.29 | 0.20 | 0.29 | 0.39 | |
| Total | 0.31 | 0.33 | 0.24 | 0.45 | 0.07 | 0.30 | 0.38 | 0.35 | 0.51 | 0.30 | 0.24 | 0.30 | 0.38 | |
|
| ||||||||||||||
| < 1 | 0.00 | 0.26 | 1.69 | 1.47 | 2.09 | 3.14 | 2.37 | 2.62 | 4.90 | 3.11 | 2.64 | 1.32 | 2.55 | |
| 1-4 | 0.93 | 0.41 | 0.52 | 0.57 | 0.93 | 0.58 | 0.90 | 1.18 | 1.95 | 0.91 | 1.09 | 0.94 | 0.50 | |
| Northeast | 5-9 | 0.63 | 0.80 | 0.41 | 0.32 | 0.68 | 0.71 | 0.87 | 0.64 | 1.45 | 1.06 | 1.01 | 1.19 | 0.53 |
| ≥ 10 | 0.17 | 0.22 | 0.11 | 0.22 | 0.25 | 0.26 | 0.28 | 0.35 | 0.48 | 0.61 | 0.50 | 0.58 | 0.41 | |
| Total | 0.29 | 0.30 | 0.20 | 0.28 | 0.38 | 0.38 | 0.42 | 0.48 | 0.76 | 0.71 | 0.62 | 0.67 | 0.46 | |
|
| ||||||||||||||
| < 1 | 4.40 | 0.00 | 3.02 | 4.88 | 5.66 | 7.22 | 8.05 | 7.64 | 9.08 | 4.53 | 2.65 | 2.39 | 1.49 | |
| 1-4 | 1.51 | 1.62 | 0.33 | 0.72 | 2.64 | 3.53 | 2.81 | 3.30 | 3.63 | 3.62 | 2.13 | 0.81 | 0.66 | |
| Midwest | 5-9 | 0.42 | 0.20 | 0.37 | 0.74 | 0.18 | 0.55 | 0.98 | 0.59 | 1.38 | 1.21 | 1.10 | 0.88 | 0.41 |
| ≥ 10 | 0.20 | 0.12 | 0.17 | 0.21 | 0.18 | 0.35 | 0.31 | 0.41 | 0.46 | 0.59 | 0.45 | 0.39 | 0.44 | |
| Total | 0.41 | 0.25 | 0.26 | 0.38 | 0.46 | 0.72 | 0.67 | 0.74 | 0.89 | 0.90 | 0.65 | 0.48 | 0.47 | |
|
| ||||||||||||||
| < 1 | 8.48 | 6.59 | 9.17 | 12.10 | 11.06 | 14.93 | 13.72 | 12.86 | 15.65 | 18.97 | 7.62 | 5.16 | 4.19 | |
| 1-4 | 4.25 | 3.59 | 4.60 | 5.87 | 5.83 | 6.17 | 5.32 | 6.97 | 7.27 | 7.90 | 6.41 | 3.38 | 1.64 | |
| Southeast | 5-9 | 1.75 | 1.85 | 1.56 | 2.75 | 2.86 | 2.75 | 2.79 | 3.48 | 3.56 | 3.96 | 3.61 | 4.10 | 3.09 |
| ≥ 10 | 0.26 | 0.34 | 0.41 | 0.57 | 0.54 | 0.56 | 0.67 | 0.82 | 0.92 | 1.05 | 1.13 | 1.10 | 0.88 | |
| Total | 0.81 | 0.80 | 0.94 | 1.29 | 1.25 | 1.32 | 1.33 | 1.59 | 1.71 | 1.92 | 1.70 | 1.51 | 1.13 | |
|
| ||||||||||||||
| < 1 | 2.24 | 1.51 | 2.77 | 5.00 | 5.26 | 3.42 | 2.05 | 4.55 | 4.20 | 4.85 | 1.32 | 0.44 | 2.79 | |
| 1-4 | 1.40 | 1.22 | 1.55 | 2.14 | 1.96 | 1.93 | 1.90 | 1.43 | 1.53 | 1.11 | 1.56 | 0.35 | 0.41 | |
| South | 5-9 | 0.29 | 0.12 | 0.60 | 1.24 | 0.60 | 1.99 | 0.62 | 0.83 | 0.23 | 0.83 | 0.69 | 0.47 | 0.26 |
| ≥ 10 | 0.20 | 0.14 | 0.18 | 0.16 | 0.25 | 0.19 | 0.17 | 0.22 | 0.19 | 0.19 | 0.19 | 0.17 | 0.18 | |
| Total | 0.32 | 0.24 | 0.35 | 0.46 | 0.47 | 0.50 | 0.34 | 0.40 | 0.32 | 0.35 | 0.32 | 0.20 | 0.23 | |
*: years in bold indicate period pos-vaccine implementation.