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. 2016 Dec 28;8(6):10050–10063. doi: 10.18632/oncotarget.14327

Figure 1. Reprogramming factors that induce pluripotency are expressed in spermatogonial progenitors except Nanog.

Figure 1

a. Klf4, c-Myc, Lin-28, Oct4, Sox2, and Nanog expression measured by flow cytometry in cultured SSCs and b. in vivo in PLZF+ undifferentiated spermatogonia. Red, negative IgG control; blue, cells of interest. Quadrants were placed according to IgG controls. c. Expression of reprogramming factors in cultured SSCs compared with MEFs and mouse embryonic stem cells (ESCs) by quantitative RT-PCR. The expression levels of SSCs and ESCs are normalized to that of MEFs. Error bars represent SEM, n=3. * P< 0.05, ** P< 0.01, *** P< 0.001.