Table 3. Analysis of SNPs associated with OS in LC patients.
| SNP | Genotype | Total N | Variables in the Equation | Median | 95% CI | Chi-Square | p b for log-rank | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Wald | HR | 95% CI | p a | |||||||
| rs10088262 | G/G (0) | 55 | 4.69 | 0.096 | 66.00 | 39.47-92.53 | ||||
| G/A (1) | 71 | 4.38 | 1.57 | 1.03-2.39 | 0.036* | 32.00 | 22.64-41.36 | |||
| A/A (2) | 34 | 0.76 | 1.57 | 0.57-4.34 | 0.382 | 32.00 | 0-87.21 | |||
| Overall | 160 | 48.00 | 30.56-65.44 | 4.84 | 0.809 | |||||
| rs1665650 | G/G (0) | 52 | 7.99 | 0.018* | 36.00 | 25.73-46.27 | ||||
| A/G (1) | 107 | 3.95 | 0.65 | 0.43-0.99 | 0.047* | 71.00 | 49.22-92.78 | |||
| A/A (2) | 7 | 2.00 | 1.98 | 0.77-5.09 | 0.157 | 18.00 | 0.04-35.94 | |||
| Overall | 166 | 48.00 | 30.54-65.46 | 8.56 | 0.014* | |||||
| rs3802842 | A/A (0) | 112 | 9.44 | 0.009* | 48.00 | 18.72-77.29 | ||||
| C/A (1) | 32 | 0.01 | 1.02 | 0.60-1.73 | 0.939 | 68.00 | 31.09-104.91 | |||
| C/C (2) | 24 | 9.03 | 2.18 | 1.31-3.61 | 0.003* | 26.00 | 9.00 -43.00 | |||
| Overall | 168 | 50.00 | 31.06-68.94 | 10.06 | 0.007* | |||||
| rs59336 | A/A (0) | 30 | 13.3 | 0.001* | 36.00 | 30.31-41.69 | ||||
| T/A (1) | 115 | 4.09 | 0.61 | 0.37-.985 | 0.043* | 68.00 | 38.56-97.44 | |||
| T/T (2) | 7 | 4.28 | 2.61 | 1.05-6.49 | 0.039* | 12.00 | 9.43-14.57 | |||
| Overall | 152 | 46.00 | 27.65-64.35 | 15.21 | <0.001* | |||||
p a for Wald test < 0.05 indicates statistical significance for individual coefficients
p b for Log-rank Test < 0.05 indicates statistical significance for grouping variables
*: indicates statistical significance