Table 1. Genes Regulated by DHT, AR and/or Src.
| Experimental Condition | Control | DHT/AR-regulated Genes |
|---|---|---|
| LNCaP + DHT | LNCaP | KLK2, IGF1R, NDRG1, SGK1, SLC5A4, SNAI2, TARP, HPGD, ELOVL7, ST6GALNAC1COL5A2, UGT2B17, UGT2B15, SI |
| VCaP + DHT | VCaP | KLK4, SLC2A5, TMPRSS2, DHCR24, AGR2VAV3, IGFBP3 |
| LNCaP[Src] | LNCaP + DHT | PGR, PIGR, DPP4, LAMC3, HGMCS2,NKX3-1, SNAI2, TARP, ATAD2, ELOVL7, GHR,, HERC3, HOMER2, HPGD, JAG1, NDRG1, SGK1, SLC4A4, ADRA2A, ANXA1, CARTPT, HMGCS2, ID3, DHCR24, ETV1, IGF1R |
| LNCaP[Src] + DHT | LNCaP[Src] | SNAI2, CARTPT, DHCR24, NKX3-1 |
| LNCaP[Src] | LNCaP | CD74, DPP4, PIP, SLC5A4,ETV1, GHR, JAG1, SI, SLC4A4, SLC22A3 |
Sampling of highest up- (red) and down-regulated (green) genes differentially regulated (threshold of log2≥3) between control and experimental conditions.