Table 4. Univariate and multivariate analyses using the Cox proportional hazards model for clinical and clinicopathological factors that affected overall survival after small cell lung cancer (SCLC) resection for SCLC.
| Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
| HRa (95%C.I.b) | P | HR (95%C.I.) | P | |
| Age (years) | ||||
| ≧65 vs. <65 | 1.035 (0.634-1.746) | 0.893 | ||
| Sex | ||||
| Male vs. Female | 1.435 (0.833-2.633) | 0.200 | ||
| Smoking history (pack-years) | ||||
| ≧20 vs. <20 | 1.107 (0.561-2.513) | 0.785 | ||
| ECOG PSc | ||||
| 1 vs. 0 | 1.618 (0.934-2.703) | 0.084 | ||
| Histlogy | ||||
| SCLCd vs. | 0.948 (0.574-1.627) | 0.840 | ||
| Combined SCLC | ||||
| pTe | ||||
| T2-4 vs. T1 | 1.666 (1.041-2.671) | 0.034 | 1.812 (1.115-2.947) | 0.017 |
| pNf | ||||
| N1-3 vs. N0 | 1.508 (0.920-2.428) | 0.102 | ||
| Adjuvant chemotherapy | ||||
| Yes vs. No | 0.524 (0.325-0.854) | 0.010 | 0.546 (0.338-0.892) | 0.016 |
| Notch1 | ||||
| High vs. Low | 0.517 (0.265-0.927) | 0.026 | 0.503 (0.255-0.913) | 0.023 |
| Numb | ||||
| High vs. Low | 1.367 (0.856-2.186) | 0.190 | ||
a Hazard ratio.
b Confidence interval.
c Eastern Cooperative Oncology Group performance status.
d Small cell lung cancer.
e Pathological tumor classification.
f Pathological lymph node status.