Skip to main content
. 2017 Jan 3;8(6):9035–9052. doi: 10.18632/oncotarget.14764

Figure 13. XBPi-transfection affected the surface phenotype and cytokines secretion of splenic DC in mice.

Figure 13

Splenic DCs were isolated with CD11c+ MicroBeads from mice model on PBD1 and cultured at 37°C in a humidified atmosphere with 5% CO2 overnight. A. The expression of co-stimulatory molecules including CD80, CD86 and MHC-II on surface of DCs was determined by flow cytometry and analyzed by the ratios to normal value in the same batch. B. Protein level of TNF-α and IL-12 in cell culture medium was determined with ELISA. Results were shown in mean ± SD (n = 4). * Statistically significant difference when compared with sham group (p < 0.05). & Statistically significant difference when compared XBPi with WT or NTi group (p < 0.05).