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. 2016 Nov 10;8(6):9123–9133. doi: 10.18632/oncotarget.13265

Figure 3. Histone deacetylase (HDAC) enzyme activity, histone H3 and H4 acetylation by HDACIs.

Figure 3

(A) CKD5 strongly decreases the enzyme activities by approximately 6- to 8-fold at 24 h, which was stable at 48 h in all glioblastoma cells. (B) CKD5 induces the acetylation status of histone H3 (Ac-H3) at 24 and 48 h.